The recognition of
the complexity of flow cytometric analysis has caused many journals
and granting organizations to scrutinize flow data. Thus the core flow
lab is becoming an important research resource as well as service provider
and a prudent investment for academic institutions. The challenge for
the academic core facility is to meet both the scientific and technical
mission by providing high quality services in a cost-effective and timely
manner. Serving 120+ investigators on the Chicago and Evanston Campuses, with 2 sorters and 6 benchtop analyzers
with 16+ color capabilities, we have developed a paradigm to balance
productivity with quality to minimize the cost per research project,
keep overall costs contained, and provide the necessary scientific support.
Central to this paradigm is a close working relationship with investigators
to define their projects in the early stages of development to make
optimal and efficient use of flow cytometry. In addition to high quality
and well maintained instrumentation, success of this approach requires
focused efforts in three major areas: 1) education of ALL users (faculty
and staff) in the science and technology of flow cytometry, 2) active
involvement in the scientific development of the project, 3) continuing
education for core staff.
ALL MANUSCRIPTS AND GRANTS PRESENTING WORK SUPPORTED BY THIS CORE SHOULD INCLUDE THE FOLLOWING ACKNOWLEDGEMENT
This work was supported by the Northwestern University Flow Cytometry Facility and a Cancer Center Support Grant (NCI CA060553).