
Figure 6: Multiparameter
apoptosis assessment-mitochondrial membrane potential plus Annexin V.
K562 cells (treated with STI571 or not) incubated with CMX Rosamine, washed
and resuspended in 1x binding buffer plus Annexin V FITC. Cells
undergoing apoptosis show first a loss in mitochondrial membrane potential
(loss of CMX Rosamine fluorescence) followed by a transition to Annexin
V positivity.
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